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A phase I/II study of bevacizumab, irinotecan and erlotinib in children with progressive diffuse intrinsic pontine glioma

INTRODUCTION: This study investigates the safety, tolerability, and preliminary efficacy of combined treatment with VEGF inhibitor bevacizumab, topoisomerase I inhibitor irinotecan, and EGFR inhibitor erlotinib in children with progressive diffuse intrinsic pontine glioma (DIPG). METHODS: Biweekly b...

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Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: El-Khouly, Fatma E., Veldhuijzen van Zanten, Sophie E. M., Jansen, Marc H. A., Bakker, Dewi P., Sanchez Aliaga, Esther, Hendrikse, N. Harry, Vandertop, W. Peter, van Vuurden, Dannis G., Kaspers, Gertjan J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8211596/
https://ncbi.nlm.nih.gov/pubmed/33963476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-021-03763-1
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