A phase I/II study of bevacizumab, irinotecan and erlotinib in children with progressive diffuse intrinsic pontine glioma

INTRODUCTION: This study investigates the safety, tolerability, and preliminary efficacy of combined treatment with VEGF inhibitor bevacizumab, topoisomerase I inhibitor irinotecan, and EGFR inhibitor erlotinib in children with progressive diffuse intrinsic pontine glioma (DIPG). METHODS: Biweekly b...

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Udgivet i:J Neurooncol
Main Authors: El-Khouly, Fatma E., Veldhuijzen van Zanten, Sophie E. M., Jansen, Marc H. A., Bakker, Dewi P., Sanchez Aliaga, Esther, Hendrikse, N. Harry, Vandertop, W. Peter, van Vuurden, Dannis G., Kaspers, Gertjan J. L.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2021
Fag:
Clinical Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8211596/
https://ncbi.nlm.nih.gov/pubmed/33963476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-021-03763-1
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