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Amyloid-Beta Mediates Homeostatic Synaptic Plasticity

The physiological role of the amyloid-precursor protein (APP) is insufficiently understood. Recent work has implicated APP in the regulation of synaptic plasticity. Substantial evidence exists for a role of APP and its secreted ectodomain APPsα in Hebbian plasticity. Here, we addressed the relevance...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Galanis, Christos, Fellenz, Meike, Becker, Denise, Bold, Charlotte, Lichtenthaler, Stefan F., Müller, Ulrike C., Deller, Thomas, Vlachos, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8211553/
https://ncbi.nlm.nih.gov/pubmed/33926999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1820-20.2021
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