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The bioactivity of soluble Fas ligand is modulated by key amino acids of its stalk region

We have previously reported that the 26-amino acid N-terminus stalk region of soluble Fas ligand (sFasL), which is separate from its binding site, is required for its biological function. Here we investigate the mechanisms that link the structure of the sFasL stalk region with its function. Using si...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Kajikawa, Osamu, Herrero, Raquel, Chow, Yu-Hua, Hung, Chi F., Matute-Bello, Gustavo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8211282/
https://ncbi.nlm.nih.gov/pubmed/34138914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0253260
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