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Flavonoid GL-V9 suppresses invasion and migration of human colorectal cancer cells by inhibiting PI3K/Akt and MMP-2/9 signaling

Tumor distant metastasis is the primary cause of death in colorectal cancer (CRC) patients. GL-V9 is a newly synthesized flavonoid derivative with several beneficial biological functions including anti-tumor and anti-inflammation. However, the anti-metastatic effect of GL-V9 and related mechanisms i...

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Podrobná bibliografie
Vydáno v:J Cancer
Hlavní autoři: Gu, Ye, Yu, Jiejie, Ding, Cong, Zhou, Yifeng, Yang, Jiangfeng, Yu, WeiPing, Zhang, Xiaofeng, Huang, Haitao
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8210567/
https://ncbi.nlm.nih.gov/pubmed/34149918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.58710
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