Doxorubicin induces an alarmin-like TLR4-dependent autocrine/paracrine action of Nucleophosmin in human cardiac mesenchymal progenitor cells

BACKGROUND: Doxorubicin (Dox) is an anti-cancer anthracycline drug that causes double-stranded DNA breaks. It is highly effective against several types of tumours; however, it also has adverse effects on regenerative populations of normal cells, such as human cardiac mesenchymal progenitor cells (hC...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Beji, Sara, D’Agostino, Marco, Gambini, Elisa, Sileno, Sara, Scopece, Alessandro, Vinci, Maria Cristina, Milano, Giuseppina, Melillo, Guido, Napolitano, Monica, Pompilio, Giulio, Capogrossi, Maurizio C., Avitabile, Daniele, Magenta, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8210386/
https://ncbi.nlm.nih.gov/pubmed/34134693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-021-01058-5
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