Global identification and characterization of tRNA-derived RNA fragment landscapes across human cancers

Transfer RNA-derived RNA fragments (tRFs) are a class of small non-coding RNAs that are abundant in many organisms, but their role in cancer has not been fully explored. Here, we report a functional genomic landscape of tRFs in 8118 specimens across 15 cancer types from The Cancer Genome Atlas. Thes...

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Vydáno v:NAR Cancer
Hlavní autoři: Sun, Xiwei, Yang, Juze, Yu, Mengqian, Yao, Dongxia, Zhou, Liyuan, Li, Xufan, Qiu, Qiongzi, Lin, Weiqiang, Lu, Bingjian, Chen, Enguo, Wang, Ping, Chen, Wantao, Tao, Sifeng, Xu, Haiming, Williams, Anna, Liu, Yong, Pan, Xiaoqing, Cowley, Allen W, Lu, Weiguo, Liang, Mingyu, Liu, Pengyuan, Lu, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Cancer Genomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8210304/
https://ncbi.nlm.nih.gov/pubmed/34316691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcaa031
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