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Homologous recombination, cancer and the ‘RAD51 paradox’
Genetic instability is a hallmark of cancer cells. Homologous recombination (HR) plays key roles in genome stability and variability due to its roles in DNA double-strand break and interstrand crosslink repair, and in the protection and resumption of arrested replication forks. HR deficiency leads t...
Tallennettuna:
| Julkaisussa: | NAR Cancer |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2021
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8209977/ https://ncbi.nlm.nih.gov/pubmed/34316706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcab016 |
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