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The DNA damage inducible lncRNA SCAT7 regulates genomic integrity and topoisomerase 1 turnover in lung adenocarcinoma

Despite the rapid improvements in unveiling the importance of lncRNAs in all aspects of cancer biology, there is still a void in mechanistic understanding of their role in the DNA damage response. Here we explored the potential role of the oncogenic lncRNA SCAT7 (ELF3-AS1) in the maintenance of geno...

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Détails bibliographiques
Publié dans:NAR Cancer
Auteurs principaux: Statello, Luisa, Ali, Mohamad M, Reischl, Silke, Mahale, Sagar, Kosalai, Subazini Thankaswamy, Huarte, Maite, Kanduri, Chandrasekhar
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209975/
https://ncbi.nlm.nih.gov/pubmed/34316698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcab002
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