Cytochrome P450-mediated 17β-estradiol metabolism in zebrafish (Danio rerio)

Cytochrome P4501 (CYP1) and CYP3A proteins are primarily responsible for the metabolism of 17β-estradiol (E(2)) in mammals. We have cloned and heterologously expressed CYP1A, CYP1B1, CYP1C1, CYP1C2, CYP1D1, and CYP3A65 from zebrafish (Danio rerio) to determine the CYP-mediated metabolism of E(2) in...

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Udgivet i:J Endocrinol
Main Authors: Scornaienchi, Marcus L, Thornton, Cammi, Willett, Kristine L, Wilson, Joanna Y
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209656/
https://ncbi.nlm.nih.gov/pubmed/20522564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-10-0075
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