3,3’-Diindolylmethane Enhances Paclitaxel Sensitivity by Suppressing DNMT1-Mediated KLF4 Methylation in Breast Cancer

Paclitaxel (PTX) is a first-line chemotherapeutic drug for the treatment of breast cancer, but drug resistance seriously limits its clinical use. The aim of the present work was to explore the effect of 3,3’-diindolylmethane (DIM) on PTX sensitivity and its possible mechanism in breast cancer. The e...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Xiang, Fenfen, Zhu, Zhaowei, Zhang, Mengzhe, Wang, Jie, Chen, Zixi, Li, Xiaoxiao, Zhang, Tao, Gu, Qing, Wu, Rong, Kang, Xiangdong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209418/
https://ncbi.nlm.nih.gov/pubmed/34150611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.627856
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge