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β-Arrestin2 deficiency attenuates oxidative stress in mouse hepatic fibrosis through modulation of NOX4

Hepatic fibrosis is a disease characterized by excessive deposition of extracellular matrix (ECM) in the liver. Activation of hepatic stellate cells (HSCs) is responsible for most of ECM production. Oxidative stress and reactive oxygen species (ROS) may be important factors leading to liver fibrosis...

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Bibliografske podrobnosti
izdano v:Acta Pharmacol Sin
Main Authors: Du, Jia-jia, Sun, Jia-chang, Li, Nan, Li, Xiu-qin, Sun, Wu-yi, Wei, Wei
Format: Artigo
Jezik:Inglês
Izdano: Springer Singapore 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209231/
https://ncbi.nlm.nih.gov/pubmed/33116250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-00545-9
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