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Prospective randomized pharmacogenetic study of topiramate for treating alcohol use disorder

In a prior study, topiramate reduced heavy drinking among individuals who sought to reduce their drinking, with the effect moderated by a single nucleotide polymorphism (SNP; rs2832407) in GRIK1, which encodes the kainate GluK1 receptor subunit (Kranzler et al. 2014). The present study sought to rep...

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Vydáno v:Neuropsychopharmacology
Hlavní autoři: Kranzler, Henry R., Morris, Paige E., Pond, Timothy, Crist, Richard C., Kampman, Kyle M., Hartwell, Emily E., Lynch, Kevin G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209023/
https://ncbi.nlm.nih.gov/pubmed/33568796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-00945-9
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