A modified in vitro clot lysis assay predicts outcomes and safety in acute ischemic stroke patients undergoing intravenous thrombolysis

The outcome of intravenous thrombolysis using recombinant tissue plasminogen activator (rt-PA) is only favorable in ≈ 40% of acute ischemic stroke (AIS) patients. Moreover, in ≈ 6–8% of cases, intracerebral hemorrhage (ICH) develops. We tested whether a modification of clot lysis assay (CLA), might...

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Udgivet i:Sci Rep
Main Authors: Orbán-Kálmándi, Rita, Szegedi, István, Sarkady, Ferenc, Fekete, István, Fekete, Klára, Vasas, Nikolett, Berényi, Ervin, Csiba, László, Bagoly, Zsuzsa
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208992/
https://ncbi.nlm.nih.gov/pubmed/34135389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92041-1
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