SIRT2‐knockdown rescues GARS‐induced Charcot‐Marie‐Tooth neuropathy

Charcot‐Marie‐Tooth disease is the most common inherited peripheral neuropathy. Dominant mutations in the glycyl‐tRNA synthetase (GARS) gene cause peripheral nerve degeneration and lead to CMT disease type 2D. The underlying mechanisms of mutations in GARS (GARS(CMT2D)) in disease pathogenesis are n...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Zhao, Yingying, Xie, Liangguo, Shen, Chao, Qi, Qian, Qin, Yicai, Xing, Juan, Zhou, Dejian, Qi, Yun, Yan, Zhiqiang, Lin, Xinhua, Dai, Rongyang, Lin, Jinzhong, Yu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208790/
https://ncbi.nlm.nih.gov/pubmed/34053152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13391
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