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Quantification of spatial tumor heterogeneity in immunohistochemistry staining images

MOTIVATION: Quantitative immunofluorescence is often used for immunohistochemistry quantification of proteins that serve as cancer biomarkers. Advanced image analysis systems for pathology allow capturing expression levels in each individual cell or subcellular compartment. However, only the mean si...

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Publicat a:Bioinformatics
Autors principals: Chervoneva, Inna, Peck, Amy R, Yi, Misung, Freydin, Boris, Rui, Hallgeir
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208754/
https://ncbi.nlm.nih.gov/pubmed/33275142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa965
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