Immunization with cytomegalovirus envelope glycoprotein M and glycoprotein N DNA vaccines can provide mice with complete protection against a lethal murine cytomegalovirus challenge

Human cytomegalovirus virions contain three major glycoprotein complexes (gC I, II, III), all of which are required for CMV infectivity. These complexes also represent major antigenic targets for anti-viral immune responses. The gC II complex consists of two glycoproteins, gM and gN. In the current...

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Detalles Bibliográficos
Publicado en:Virol Sin
Autores principales: Wang, Huadong, Yao, Yanfeng, Huang, Chaoyang, Chen, Quanjiao, Chen, Jianjun, Chen, Ze
Formato: Artigo
Lenguaje:Inglês
Publicado: SP Wuhan Institute of Virology, CAS 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208358/
https://ncbi.nlm.nih.gov/pubmed/23715998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-013-3330-9
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