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D3R Grand Challenge 4: Ligand similarity and MM-GBSA-based pose prediction and affinity ranking for BACE-1 inhibitors

The Drug Design Data Resource (D3R) Grand Challenges present an opportunity to assess, in the context of a blind predictive challenge, the accuracy and the limits of tools and methodologies designed to help guide pharmaceutical drug discovery projects. Here, we report the results of our participatio...

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Detalhes bibliográficos
Publicado no:J Comput Aided Mol Des
Main Authors: Sasmal, Sukanya, Khoury, Léa El, Mobley, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208075/
https://ncbi.nlm.nih.gov/pubmed/31781990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-019-00249-1
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