Incidental identification of inv(16)(p13.1q22)/CBFB–MYH11 variant transcript in a patient with therapy-related acute myeloid leukemia by routine leukemia translocation panel screen: implications for diagnosis and therapy

A 52-yr-old woman presented with therapy-related acute myeloid leukemia. A bone marrow biopsy showed 21% blasts with a myeloid phenotype and no other notable features such as abnormal eosinophils. Routine nanofluidics-based reverse transcriptase polymerase chain reaction (PCR) leukemia translocation...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Mol Case Stud
Main Authors: Quesada, Andrés E., Luthra, Rajyalakshmi, Jabbour, Elias, Patel, Keyur P., Khoury, Joseph D., Tang, Zhenya, Alvarez, Hector, Mallampati, Saradhi, Garcia-Manero, Guillermo, Montalban-Bravo, Guillermo, Medeiros, L. Jeffrey, Kanagal-Shamanna, Rashmi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208042/
https://ncbi.nlm.nih.gov/pubmed/34117074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a006084
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