High Expression of Cancer-IgG Is Associated With Poor Prognosis and Radioresistance via PI3K/AKT/DNA-PKcs Pathway Regulation in Lung Adenocarcinoma

BACKGROUND: Lung adenocarcinoma (LUAD) is the dominant type of lung neoplasms, and radiotherapy is its mainstay treatment, yet poor prognosis caused by radioresistance remains problematic. Cancer-derived immunoglobulin G (cancer-IgG) has been detected in multiple cancers and plays important roles in...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Yang, Xiongtao, Wang, Guohui, You, Jing, Gu, Runchuan, Xu, Xiaohong, Xu, Changdan, Wang, Hao, Zhao, Ruisong, Qiu, Xiaoyan, Zhu, Guangying
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208032/
https://ncbi.nlm.nih.gov/pubmed/34150640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.675397
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