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GRASP55 senses glucose deprivation through O-GlcNAcylation to promote autophagosome-lysosome fusion

The Golgi apparatus is the central hub for protein trafficking and glycosylation in the secretory pathway. However, how the Golgi responds to glucose deprivation is so far unknown. Here, we report that GRASP55, the Golgi stacking protein located in medial- and trans-Golgi cisternae, is O-GlcNAcylate...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Zhang, Xiaoyan, Wang, Leibin, Lak, Behnam, Li, Jie, Jokitalo, Eija, Wang, Yanzhuang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207546/
https://ncbi.nlm.nih.gov/pubmed/29689198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.03.023
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