Association of Polymorphisms in T-Cell Activation Costimulatory/Inhibitory Signal Genes With Allograft Kidney Rejection Risk

The genes CD28, CD86 and CTLA-4 conform the costimulatory (CD28-CD86) or inhibitory (CTLA-4-CD86) signal in T-cell activation. T-cell immune response has a critical role in allograft rejection, and single nucleotide polymorphisms (SNPs) located in these genes have been widely analyzed with controver...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Santiago, Jose Luis, Sánchez-Pérez, Luis, Pérez-Flores, Isabel, de la Higuera, Maria Angeles Moreno, Romero, Natividad Calvo, Querol-García, Javier, Urcelay, Elena, Sánchez-Fructuoso, Ana Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206554/
https://ncbi.nlm.nih.gov/pubmed/34149691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.650979
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