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Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration

Macular degeneration (MD) is characterized by the progressive deterioration of the macula and represents one of the most prevalent causes of blindness worldwide. Abnormal intracellular accumulation of lipid droplets and pericellular deposits of lipid-rich material in the retinal pigment epithelium (...

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Dettagli Bibliografici
Pubblicato in:Am J Hum Genet
Autori principali: Tsai, Yi-Ting, Li, Yao, Ryu, Joseph, Su, Pei-Yin, Cheng, Chia-Hua, Wu, Wen-Hsuan, Li, Yong-Shi, Quinn, Peter M.J., Leong, Kam W., Tsang, Stephen H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206198/
https://ncbi.nlm.nih.gov/pubmed/33909993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2021.04.006
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