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Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release
Human neutrophils constitutively express high amounts of arginase-1, which depletes arginine from the surrounding medium and downregulates T-cell activation. Here, we have found that neutrophil arginase-1, released from activated human neutrophils or dead cells, induced apoptosis in cancer cells thr...
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| Yayımlandı: | Sci Rep |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8206108/ https://ncbi.nlm.nih.gov/pubmed/34131176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91947-0 |
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