Drug-specific Treg cells are induced during desensitization procedure for rituximab and tocilizumab in patients with anaphylaxis

Biologic agents (BA) are able to induce an adaptive immune response in a proportion of exposed patients with the onset of anti-drug antibodies (ADA), which are usually responsible for hypersensitivity reactions (HR). Drug desensitization (DD) for BA allows transient clinical tolerance to the drug in...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Vultaggio, Alessandra, Nencini, Francesca, Bormioli, Susanna, Silvestri, Elena, Dies, Laura, Vivarelli, Emanuele, Maggi, Enrico, Matucci, Andrea
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206099/
https://ncbi.nlm.nih.gov/pubmed/34131173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91851-7
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