CRISPLD2 attenuates pro-inflammatory cytokines production in HMGB1-stimulated monocytes and septic mice

HMGB1 has been identified as a pro-inflammatory mediator which leads to sepsis lethality. Previous studies suggested that CRISPLD2 had anti-inflammatory property and might severe as a therapeutic agent in sepsis. In the present study, we first conducted bioinformatic analysis to explore the expressi...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Zhang, Sheng, Pei, Lei, Qu, Jinlong, Sun, Lizhu, Jiang, Weiwei, Li, Wenfang, Lin, Zhaofen, Chen, Dechang
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2021
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205833/
https://ncbi.nlm.nih.gov/pubmed/34150000
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