A functional autophagy pathway is essential for BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs)

Mesenchymal stem cells (MSCs) are capable of differentiating into bone, cartilage and adipose tissues. We identified BMP9 as the most potent osteoinductive BMP although detailed mechanism underlying BMP9-regulated osteogenesis of MSCs is indeterminate. Emerging evidence indicates that autophagy play...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Zhao, Xia, Huang, Bo, Wang, Hao, Ni, Na, He, Fang, Liu, Qing, Shi, Deyao, Chen, Connie, Zhao, Piao, Wang, Xi, Wagstaff, William, Pakvasa, Mikhail, Tucker, Andrew Blake, Lee, Michael J, Wolf, Jennifer Moriatis, Reid, Russell R, Hynes, Kelly, Strelzow, Jason, Ho, Sherwin H, Yu, Tengbo, Yang, Jian, Shen, Le, He, Tong-Chuan, Zhang, Yongtao
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205769/
https://ncbi.nlm.nih.gov/pubmed/34150011
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