Polymerization of misfolded Z alpha-1 antitrypsin protein lowers CX3CR1 expression in human PBMCs

Expression levels of CX3CR1 (C-X3-C motif chemokine receptor 1) on immune cells have significant importance in maintaining tissue homeostasis under physiological and pathological conditions. The factors implicated in the regulation of CX3CR1 and its specific ligand CX3CL1 (fractalkine) expression re...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Tumpara, Srinu, Ballmaier, Matthias, Wrenger, Sabine, König, Mandy, Lehmann, Matthias, Lichtinghagen, Ralf, Martinez-Delgado, Beatriz, Korenbaum, Elena, DeLuca, David, Jedicke, Nils, Welte, Tobias, Fromme, Malin, Strnad, Pavel, Stolk, Jan, Janciauskiene, Sabina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2021
Aiheet:
Cell Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205483/
https://ncbi.nlm.nih.gov/pubmed/34002692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64881
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