In Vivo Diagnosis of Synucleinopathies: A Comparative Study of Skin Biopsy and RT-QuIC

OBJECTIVE: To determine whether (1) immunofluorescence is a reproducible technique in detecting misfolded α-synuclein in skin nerves and subsequently whether (2) immunofluorescence and real-time quaking-induced conversion (RT-QuIC) (both in skin and CSF) show a comparable in vivo diagnostic accuracy...

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Bibliografiske detaljer
Udgivet i:Neurology
Main Authors: Donadio, Vincenzo, Wang, Zerui, Incensi, Alex, Rizzo, Giovanni, Fileccia, Enrico, Vacchiano, Veria, Capellari, Sabina, Magnani, Martina, Scaglione, Cesa, Stanzani Maserati, Michelangelo, Avoni, Patrizia, Liguori, Rocco, Zou, Wenquan
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205473/
https://ncbi.nlm.nih.gov/pubmed/33837116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000011935
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