Proteomics and Transcriptomics of the Hippocampus and Cortex in SUDEP and High-Risk SUDEP Patients

OBJECTIVE: To identify the molecular signaling pathways underlying sudden unexpected death in epilepsy (SUDEP) and high-risk SUDEP compared to control patients with epilepsy. METHODS: For proteomics analyses, we evaluated the hippocampus and frontal cortex from microdissected postmortem brain tissue...

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Publicado no:Neurology
Main Authors: Leitner, Dominique F., Mills, James D., Pires, Geoffrey, Faustin, Arline, Drummond, Eleanor, Kanshin, Evgeny, Nayak, Shruti, Askenazi, Manor, Verducci, Chloe, Chen, Bei Jun, Janitz, Michael, Anink, Jasper J., Baayen, Johannes C., Idema, Sander, van Vliet, Erwin A., Devore, Sasha, Friedman, Daniel, Diehl, Beate, Scott, Catherine, Thijs, Roland, Wisniewski, Thomas, Ueberheide, Beatrix, Thom, Maria, Aronica, Eleonora, Devinsky, Orrin
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205452/
https://ncbi.nlm.nih.gov/pubmed/33910938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000011999
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