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Activity-mediated accumulation of potassium induces a switch in firing pattern and neuronal excitability type
During normal neuronal activity, ionic concentration gradients across a neuron’s membrane are often assumed to be stable. Prolonged spiking activity, however, can reduce transmembrane gradients and affect voltage dynamics. Based on mathematical modeling, we investigated the impact of neuronal activi...
Uloženo v:
| Vydáno v: | PLoS Comput Biol |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8205125/ https://ncbi.nlm.nih.gov/pubmed/34043638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008510 |
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