β-cyclodextrin chitosan-based hydrogels with tunable pH-responsive properties for controlled release of acyclovir: design, characterization, safety, and pharmacokinetic evaluation

In this work, series of pH-responsive hydrogels (FMA1–FMA9) were synthesized, characterized, and evaluated as potential carrier for oral delivery of an antiviral drug, acyclovir (ACV). Different proportions of β-cyclodextrin (β-CD), chitosan (CS), methacrylic acid (MAA) and N′ N′-methylenebis-acryla...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Malik, Nadia Shamshad, Ahmad, Mahmood, Alqahtani, Mohammed S., Mahmood, Arshad, Barkat, Kashif, Khan, Muhammad Tariq, Tulain, Ume Ruqia, Rashid, Ayesha
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205001/
https://ncbi.nlm.nih.gov/pubmed/34114907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2021.1921074
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