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ATG4-family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system

In eukaryotes, ATG4/Atg4 is a critical regulator of macroautophagy/autophagy. The protease activity of Atg4/ATG4, involved in conjugation and deconjugation of Atg8-family proteins, was so far regarded as its sole functional contribution. However, the role of individual ATG4-family proteins during ma...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Lahiri, Vikramjit, Klionsky, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204968/
https://ncbi.nlm.nih.gov/pubmed/34011239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2021.1917284
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