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Overall survival in metastatic melanoma correlates with pembrolizumab exposure and T cell exhaustion markers

Trial data support an absence of an exposure–survival relationship for pembrolizumab. As these relationships remain unexamined in a real‐world setting, we determined them in metastatic melanoma prospectively in an observational study. Translational objectives included identifying biomarkers of progr...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Navani, Vishal, Graves, Moira C., Marchett, Giovana Celli, Mandaliya, Hiren, Bowden, Nikola A., van der Westhuizen, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204864/
https://ncbi.nlm.nih.gov/pubmed/34129290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.808
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