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A Rationally Designed Micellar Nanocarrier for the Delivery of Hydrophilic Methotrexate in Psoriasis Treatment

Methotrexate (MTX) is broadly applied in the clinic for the treatments of cancers and autoimmune diseases. Targeted delivery of MTX is attractive to improve its efficacy and reduce off-target toxicity. However, MTX encapsulation in nanoparticle is challenging due to its high water solubility. We rat...

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Detaylı Bibliyografya
Yayımlandı:ACS Appl Bio Mater
Asıl Yazarlar: Guo, Dandan, Shi, Changying, Wang, Lili, Ji, Xiaotian, Zhang, Shengle, Luo, Juntao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204631/
https://ncbi.nlm.nih.gov/pubmed/34136761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsabm.0c00342
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