Type I IFN signaling limits hemorrhage-like disease after infection with Japanese encephalitis virus through modulating a prerequisite infection of CD11b(+)Ly-6C(+) monocytes

BACKGROUND: The crucial role of type I interferon (IFN-I, IFN-α/β) is well known to control central nervous system (CNS) neuroinflammation caused by neurotrophic flaviviruses such as Japanese encephalitis virus (JEV) and West Nile virus. However, an in-depth analysis of IFN-I signal-dependent cellul...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Patil, Ajit Mahadev, Choi, Jin Young, Park, Seong Ok, Uyangaa, Erdenebelig, Kim, Bumseok, Kim, Koanhoi, Eo, Seong Kug
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204625/
https://ncbi.nlm.nih.gov/pubmed/34130738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02180-5
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