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Intrachain interaction topology can identify functionally similar intrinsically disordered proteins

Functionally similar IDPs (intrinsically disordered proteins) often have little sequence similarity. This is in stark contrast to folded proteins and poses a challenge for the inverse problem, functional classification of IDPs using sequence alignment. The problem is further compounded because of th...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Huihui, Jonathan, Ghosh, Kingshuk
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204386/
https://ncbi.nlm.nih.gov/pubmed/33865811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.11.2282
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