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Residence time analysis of RNA polymerase transcription dynamics: A Bayesian sticky HMM approach
The time spent by a single RNA polymerase (RNAP) at specific locations along the DNA, termed “residence time,” reports on the initiation, elongation, and termination stages of transcription. At the single-molecule level, this information can be obtained from dual ultrastable optical trapping experim...
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| Veröffentlicht in: | Biophys J |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8204346/ https://ncbi.nlm.nih.gov/pubmed/33705761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.02.045 |
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