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Solution structure of deglycosylated human IgG1 shows the role of C(H)2 glycans in its conformation
The human immunoglobulin G (IgG) class is the most prevalent antibody in serum, with the IgG1 subclass being the most abundant. IgG1 is composed of two Fab regions connected to a Fc region through a 15-residue hinge peptide. Two glycan chains are conserved in the Fc region in IgG; however, their imp...
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| Yayımlandı: | Biophys J |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Biophysical Society
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8204293/ https://ncbi.nlm.nih.gov/pubmed/33675758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.02.038 |
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