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Structural determinants of cholesterol recognition in helical integral membrane proteins

Cholesterol is an integral component of mammalian membranes. It has been shown to modulate membrane fluidity and dynamics and alter integral membrane protein function. However, understanding the molecular mechanisms of how cholesterol impacts protein function is complicated by limited and conflictin...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Marlow, Brennica, Kuenze, Georg, Li, Bian, Sanders, Charles R., Meiler, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204209/
https://ncbi.nlm.nih.gov/pubmed/33640379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.02.028
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