Tumor Genotyping and Homologous Recombination Repair Gene Variants in Patients With Epithelial Ovarian Cancer: Is Pathogenic Enough?

Our hypothesis was that the predictive accuracy of pathogenic variants in genes participating in the homologous recombination repair (HRR) system in patients with epithelial ovarian cancer (EOC) could be improved by considering additional next-generation sequencing (NGS) metrics. NGS genotyping was...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Fountzilas, Elena, Kotoula, Vassiliki, Koliou, Georgia-Angeliki, Liontos, Michalis, Papadopoulou, Kyriaki, Giannoulatou, Eleni, Papanikolaou, Alexios, Tikas, Ioannis, Chrisafi, Sofia, Mauri, Davide, Chatzopoulos, Kyriakos, Fostira, Florentia, Pectasides, Dimitrios, Oikonomopoulos, Georgios, Aivazi, Dimitra, Andrikopoulou, Angeliki, Visvikis, Anastasios, Aravantinos, Gerasimos, Zagouri, Flora, Fountzilas, George
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204021/
https://ncbi.nlm.nih.gov/pubmed/34141624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.683057
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