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Terminal Deoxynucleotidyl Transferase Mediated Production of Labeled Probes for Single-molecule FISH or RNA Capture

Arrays of short, singly-labeled ssDNA oligonucleotides enable in situ hybridization with single molecule sensitivity and efficient transcript specific RNA capture. Here, we describe a simple, enzymatic protocol that can be carried out using basic laboratory equipment to convert arrays of PCR oligos...

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Bibliografiske detaljer
Udgivet i:Bio Protoc
Main Authors: Gaspar, Imre, Wippich, Frank, Ephrussi, Anne
Format: Artigo
Sprog:Inglês
Udgivet: Bio-Protocol 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203885/
https://ncbi.nlm.nih.gov/pubmed/34179277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2750
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