Pre-transplant donor-reactive IL-21 producing T cells as a tool to identify an increased risk for acute rejection

Pre-transplant screening focuses on the detection of anti-HLA alloantibodies. Previous studies have shown that IFN-γ and IL-21 producing T cells are associated with the development of acute rejection (AR). The aim of this study, was to assess whether pre-transplant donor-reactive T cells and/or B ce...

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Published in:Sci Rep
Main Authors: Mendoza Rojas, Aleixandra, van Gelder, Teun, de Kuiper, Ronella, Reijerkerk, Derek, Clahsen-van Groningen, Marian C., Hesselink, Dennis A., Baan, Carla C., van Besouw, Nicole M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203783/
https://ncbi.nlm.nih.gov/pubmed/34127739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91967-w
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