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Pseudogene ACTBP2 increases blood–brain barrier permeability by promoting KHDRBS2 transcription through recruitment of KMT2D/WDR5 in Aβ(1–)(42) microenvironment

The blood–brain barrier (BBB) has a vital role in maintaining the homeostasis of the central nervous system (CNS). Changes in the structure and function of BBB can accelerate Alzheimer’s disease (AD) development. β-Amyloid (Aβ) deposition is the major pathological event of AD. We elucidated the func...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Death Discov
Asıl Yazarlar: Liu, Qianshuo, Liu, Xiaobai, Zhao, Defeng, Ruan, Xuelei, Su, Rui, Shang, Xiuli, Wang, Di, Yang, Chunqing, Xue, Yixue
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203645/
https://ncbi.nlm.nih.gov/pubmed/34127651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00531-y
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