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Caldesmon ablation in mice causes umbilical herniation and alters contractility of fetal urinary bladder smooth muscle

The actin-, myosin-, and calmodulin-binding protein caldesmon (CaD) is expressed in two splice isoforms: h-CaD, which is an integral part of the actomyosin domain of smooth muscle cells, and l-CaD, which is widely expressed and is involved in many cellular functions. Despite extensive research for m...

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Pubblicato in:J Gen Physiol
Autori principali: Pütz, Sandra, Barthel, Lisa Sophie, Frohn, Marina, Metzler, Doris, Barham, Mohammed, Pryymachuk, Galyna, Trunschke, Oliver, Lubomirov, Lubomir T., Hescheler, Jürgen, Chalovich, Joseph M., Neiss, Wolfram F., Koch, Manuel, Schroeter, Mechthild M., Pfitzer, Gabriele
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203487/
https://ncbi.nlm.nih.gov/pubmed/34115104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012776
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