IKBKB siRNA-Encapsulated Poly (Lactic-co-Glycolic Acid) Nanoparticles Diminish Neuropathic Pain by Inhibiting Microglial Activation

Activation of nuclear factor-kappa B (NF-κB) in microglia plays a decisive role in the progress of neuropathic pain, and the inhibitor of kappa B (IκB) is a protein that blocks the activation of NF-κB and is degraded by the inhibitor of NF-κB kinase subunit beta (IKBKB). The role of IKBKB is to brea...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lee, Seounghun, Shin, Hyo-Jung, Noh, Chan, Kim, Song-I, Ko, Young-Kwon, Lee, Sun-Yeul, Lim, Chaeseong, Hong, Boohwi, Yang, Sin-Young, Kim, Dong-Woon, Lee, Won-Hyung, Kim, Yoon-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203094/
https://ncbi.nlm.nih.gov/pubmed/34073390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115657
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