The nonreceptor tyrosine kinase SRMS inhibits autophagy and promotes tumor growth by phosphorylating the scaffolding protein FKBP51

Nutrient-responsive protein kinases control the balance between anabolic growth and catabolic processes such as autophagy. Aberrant regulation of these kinases is a major cause of human disease. We report here that the vertebrate nonreceptor tyrosine kinase Src-related kinase lacking C-terminal regu...

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Bibliografski detalji
Izdano u:PLoS Biol
Glavni autori: Park, Jung Mi, Yang, Seung Wook, Zhuang, Wei, Bera, Asim K., Liu, Yan, Gurbani, Deepak, von Hoyningen-Huene, Sergei J., Sakurada, Sadie Miki, Gan, Haiyun, Pruett-Miller, Shondra M., Westover, Kenneth D., Potts, Malia B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202955/
https://ncbi.nlm.nih.gov/pubmed/34077419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001281
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