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Sirt1 improves heart failure through modulating the NF-κB p65/microRNA-155/BNDF signaling cascade

Heart failure (HF) affects over 26 million people worldwide, yet the pathologies of this complex syndrome have not been completely understood. Here, we investigated the involvement of deacetylase Sirtuin 1 (Sirt1) in HF and its downstream signaling pathways. A HF model was induced by the ligation of...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Lin, Bin, Zhao, Hui, Li, Li, Zhang, Zhenzhen, Jiang, Nan, Yang, Xiaowei, Zhang, Tao, Lian, Bowen, Liu, Yaokai, Zhang, Chi, Wang, Jiaxiang, Wang, Feng, Feng, Deguang, Xu, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202895/
https://ncbi.nlm.nih.gov/pubmed/33206628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103640
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