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Silencing lncRNA XIST exhibits antiproliferative and proapoptotic effects on gastric cancer cells by up-regulating microRNA-132 and down-regulating PXN

The present study aims to elucidate the potential therapeutic role of lncRNA XIST in gastric cancer through regulation of microRNA-132 (miR-132) and paxillin (PXN) expression. The study employed 65 gastric cancer tissue specimens and SGC7901 cell lines. Our results demonstrated that expression of ln...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Aging (Albany NY)
Main Authors: Li, Ping, Wang, Liuhua, Li, Pengfei, Hu, Fangyong, Cao, Yi, Tang, Dong, Ye, Gang, Li, Hongbo, Wang, Daorong
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202840/
https://ncbi.nlm.nih.gov/pubmed/33154189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103635
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