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ChIP-seq protocol for sperm cells and embryos to assess environmental impacts and epigenetic inheritance

In the field of epigenetic inheritance, delineating molecular mechanisms implicated in the transfer of paternal environmental conditions to descendants has been elusive. This protocol details how to track sperm chromatin intergenerationally. We describe mouse model design to probe chromatin states i...

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Détails bibliographiques
Publié dans:STAR Protoc
Auteurs principaux: Lismer, Ariane, Lambrot, Romain, Lafleur, Christine, Dumeaux, Vanessa, Kimmins, Sarah
Format: Artigo
Langue:Inglês
Publié: Elsevier 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202352/
https://ncbi.nlm.nih.gov/pubmed/34159325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100602
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