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Diffusion models reveal white matter microstructural changes with ageing, pathology and cognition

White matter microstructure undergoes progressive changes during the lifespan, but the neurobiological underpinnings related to ageing and disease remains unclear. We used an advanced diffusion MRI, Neurite Orientation Dispersion and Density Imaging, to investigate the microstructural alterations du...

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Detalles Bibliográficos
Publicado en:Brain Commun
Main Authors: Raghavan, Sheelakumari, Reid, Robert I, Przybelski, Scott A, Lesnick, Timothy G, Graff-Radford, Jonathan, Schwarz, Christopher G, Knopman, David S, Mielke, Michelle M, Machulda, Mary M, Petersen, Ronald C, Jack, Clifford R, Vemuri, Prashanthi
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202149/
https://ncbi.nlm.nih.gov/pubmed/34136811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcab106
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